An appraisal of the scientific current situation and new perspectives in the treatment of cutaneous leishmaniasis

Leishmaniasis is a Neglected Tropical Diseases caused by protozoan parasites of the genus Leishmania. It major health problem in many tropical and subtropical regions world can produce three different clinical manifestations, among which cutaneous leishmaniasis has higher incidence than other forms. There are no recognized reliable means chemoprophylaxis or vaccination against infections with forms leishmaniasis. In addition, chemotherapy, unfortunately, remains, respects, unsatisfactory. Therefore, there continuing urgent need for new therapies that safe effective inducing long-term cure. This review summarizes latest advances currently available treatments improvements development drug administration. an analysis vivo assays was performed challenges facing promising strategies to treat CL discussed. The treatment will most likely evolve into approach uses multiple simultaneously reduce possibility developing resistance. continuous effort discover drugs improve leishmaniasis, but this mainly at level individual researchers. Undoubtedly, more funding needed area, as well greater participation pharmaceutical industry focus efforts on chemotherapeutic agents vaccines neglected diseases.